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- Using a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- Two F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
- In a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- The doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- Professional writer and amateur sleuth Jessica Fletcher uses her intellect, charm, and persistence to get to the bottom of every crime she encounters.
- In Las Vegas, a squad of forensic investigators are trained to solve crimes by meticulously examining the evidence. They employ advanced technology and their rationality to detect the perpetrators.
- Inside the lives of staffers in the West Wing of the White House.
- In the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- The Philadelphia homicide squad's lone female detective finds her calling when she's assigned "cold cases," older crimes that have never been solved.
- Tom Nichols is a hardened New England detective, unflinching in his pursuit of a case where nothing is as it seems and it begins to dismantle the illusions in his own life.
- A group of friends living in Beverly Hills, California make their way through life from their school days into adulthood.
- The escapades of Stan Smith, a conservative C.I.A. Agent dealing with family life, and keeping America safe.
- Gay lawyer Will and straight interior designer Grace share a New York City apartment. Their best friends are gleeful and proud gay Jack and charismatic, filthy-rich, amoral socialite Karen.
- Working for the F.B.I., a mathematician uses equations to help solve various crimes.
- A wrongfully convicted boy is sent to a brutal desert detention camp where he joins the job of digging holes for some mysterious reason.
- Deputy Police Chief Brenda Johnson runs the Priority Homicide Division of the LAPD with an unorthodox style. Her innate ability to read people and obtain confessions helps her and her team solve the city's toughest, most sensitive cases.
- Melinda Gordon, a newly married woman, possesses the gift of communicating with the dead. With her best friend Andrea's assistance, she helps the earthbound spirits to find peace and cross over.
- Two plastic surgeons--one a dedicated family man and one an unscrupulous playboy--strive to maintain their business whilst having to work their way through numerous hardships ranging from personal to clients with criminal connections.
- Three angels are sent to Earth to tell depressed and troubled people that God loves them and hasn't forgotten them.
- Five siblings raise each other following their parents' untimely deaths.
- An American police procedural television series chronicling the work of a fictional version of the Baltimore Police Department's Homicide Unit.
- Series about the special FBI Missing Persons Unit (MPU) that finds missing people by applying advanced psychological profiling to reveal the victims' lives.
- Ricky Stratton is a spoiled rich kid who lives the life that many kids dream of, but he still suffers from the problems that many teens do.
- Two divorced mothers and their children share an apartment.
- Rick Hunter is a renegade cop who bends the rules and takes justice into his own hands. Partnered with the equally stunning and rebellious Sgt. McCall, he sets out to crack down on L.A.'s slimiest criminals.