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1-14 of 14
- Kay "Kayo" O'Brien is a resident surgeon at the fictitious Manhattan General where she struggles to balance her professional and personal life. Ex-boyfriend Sam is still in the picture and she leans on nurse Rosa, her best friend.
- Wallach's best friend suffers a mild stroke but insists he doesn't need to be hospitalized; misunderstandings abound with a Sri Lankan physician anxious to learn about American surgery techniques.
- The ER is quarantined, which prevents Kayo from going to her sister's wedding, detains Doyle's accountant and jeopardizes a sick runaway.
- A street punk dukes it out with Doyle after the doctor insults his ailing mother; a male nurse learns there are drawbacks to dating Dr. O'Brien
- A second-year surgical resident deals with patients and staff at a Manhattan hospital.
- Kayo turns to an old friend for consolation after losing a patient; Cliff becomes the object of ridicule among his peers; Moffitt considers a position with another institution.
- A department-store explosion creates a major disaster as patients are rushed to Manhattan General during the midst of the Christmas season.
- Kayo treats two emergency patients: a young woman who refuses surgery for religious reasons, and a terminally ill photojournalist who wants to get the most out of his remaining days.
- Cliff puts a patient's life at risk when, concentrating more on his social life than on work, he fails to prescribe an essential medication, and Kayo takes the blame.
- A wealthy suitor brings excitement to Kayo's social life, while a stern pediatrician frustrates her life at the hospital; a psychiatrist takes an unusual interest in Cliff's genes.
- Kayo faces a dilemma in obstetrics: whether to save the life of her patient or the patient's unborn child.
- A workaholic clothing designer refuses treatment after collapsing at the hospital; without official sanction, Nat sets up shop in the linen closet to sell imported goods.
- Rosa spots a potential problem with a doctor's orders and Kayo later supports the doctor.
- A Chinatown merchant is wounded in a shootout and needs a kidney transplant, and his brain-dead assailant may be the only suitable donor; Kayo's parents breeze into town.