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- The lives of the Duggars, a Christian homeschooling family with 19 children, and how their family functions.
- A Florida medical examiner takes viewers through puzzling cases while explaining procedures and conclusions.
- Documentary-style reality show about a Pennsylvania husband, wife and each of their 8 extremely individualistic children.
- Women, who never knew they were pregnant, give birth.
- An exclusive and intimate portrait following the first pregnant man, Thomas Beatie and his wife Nancy, into the delivery room as Thomas gives birth to their baby daughter Susan.
- Dr. Jan Garavaglia has seen almost everything in 20-plus years of performing autopsies, but every once in a while there is a case that will grab her attention: the kind that bewilders pathologists.
- Older Women / Younger Men is a one-hour documentary that looks at the growing phenomenon of women dating and in many cases marrying much younger men. From the "cougar" (a predator tracking its young prey at the local bar) to women making life-long commitments to their younger partners much to the dismay of family and strangers, we examine the trials and uncertainties of these taboo relationships. Keeping the company of someone younger isn't just for men anymore!
- The true stories of doctors, patients and the fight to survive.
- About pregnant women in different circumstances ranging from being in prison to eating disorders, and how they cope.
- Duggar family spin-off special.
- This true crime series delves into the case files of the country's top forensic anthropologists and reveals the secrets trapped deep inside the human body.
- At first glance, Jonathan and Kate Gosselin seem like an ordinary young, married Pennsylvania couple. Except for the fact that they have 8 children and two sets of multiples. The couple have been married for seven years and received their first set of multiples, fraternal twins Mady and Cara, five years ago. Three years after the twins were born, they had sextuplets. The sextuplets include three boys, Aaden, Collin, and Joel, and three girls, Alexis, Hannah, and Leah. Although their life seems to be anything but normal, Jon and Kate manage to get through every day by sticking to a strict schedule and working together.
- Re-enactments and interviews with doctors and investigators combine to present stories of unusual and baffling medical cases.
- Head pathologist Coffee works at a big-city hospital helping police solve peculiar murders with the assistance of able colleagues Hudson and Mookerji and lab boy/handyman Link.
- Dr. Tom Scalea, the extraordinary physician-in-chief at the legendary Shock Trauma Center in Baltimore, leads his team to make the impossible happen to save lives. They battle death in the Trauma Resuscitation Unit and the OR.
- Everyday doctors and nurses make critical decisions to help mothers through complicated childbirth.
- SEX CHANGE HOSPITAL is a six part series based in Trinidad, Colorado, the sex change capital of the world. Each one hour episode is a self-contained journey following 2 people as they take the final step in their transition from one gender to another. Dr. Marci Bowers performs the surgeries and calls upon her own experiences as a transgender woman to guide her patients as they go through the ultimate life changing procedure.
- Silent Angels: The Rett Syndrome Story, hosted by Julia Roberts, tells about the amazing stories of families and researchers struggle leading to the discovery of the gene that causes the rare neurological disorder known as Rett syndrome.
- After a spinal cord injury made her a quadriplegic at 23, Michelle, gets pregnant at 36 and wants to give birth the natural way.
- Comedian and actor, Frank Payne, aka "The Big Guy", lends his body to science to take viewers [deep] inside his big fat body. Doctors, scientists, and engineers using the latest medical and scientific advances including state-of-the-art imaging technology, reveal the shocking truth of what more than 100 pounds of excess fat does to the body's heart, liver, bones, and joints. Featured by XIVETV.
- A talk show hosted by two sisters, both of whom are doctors, focusing on women's sexual issues and related health matters.